Arecoline Hydrobromide (ArcoFuel) (Betel Nut Extract)

1.What Is It?

Arecoline is a naturally occurring alkaloid that is derived from the betel nut, a widely used nut in Asia. The betel nut comes from the Areca leaf and is traditionally consumed by chewing in a similar manner to chewing tobacco leaves.

Arecoline Hydrobromide is the most common synthetic form of Arecoline and is trademarked under the name of "ArcoFuel". ArcoFuel has recently appeared in a number of high stimulant pre-workout supplements including Kai Greene’s DynamiK Muscle Savage RoarDana Linn Bailey’s Run Everything Labs Enter With Purpose (EWP), and Blackstone Labs' Angel Dust V2.

As with any drug there is always risk associated with high levels of use and it appears the long term heavy use of betel nut (when chewed) has been associated with the development of oral cancer. However, studies showing such a connection were conducted on mice using mega doses; 1mg of Arecoline was administered to mice 5 days per week, every week, for up to 25 months - the equivalent of approximately 250mg 5 days per week, every week for 80 years in a human. Consequently, the FDA and TGA have not indicated that there is any safety issue associated with the consumption of the synthetic extract Arecoline Hydrobromide.

2.What Does It Do?

Arecoline acts as a physical stimulant and psychoactive that can help to reduce fatigue, improve mood and increase physical performance. In particular, Arecoline acts to increase the level of acetyl-choline in the body which can result in improved perception, concentration and better overall cognitive function. 

Combined with a sensible diet and workout regime, Arecoline will help increase cognitive function and mental focus, and increase physical performance during workouts.

3.When Do I Take It?

To take advantage of the cognitive and focus benefits of Arecoline, it is best taken first thing in the morning or 15 - 30 minutes before exercise. Pre-workout supplements containing Arecoline should be taken with water before exercise. The most efficacious dose is 2 – 4  milligrams per serve.

4.How Long Does It Take To Work?

Arecoline starts working as soon as it enters the bloodstream, which is typically 15 – 30 minutes after consumption. Users can expect to experience an increase in energy and mental alertness within this time-frame. 

Some research has indicated that arecoline is as addictive as nicotine found in tobacco. As such, users may experience feelings of strong dependence on Arecoline. Mild withdrawal symptoms including fatigue, nervousness and trouble with concentration have been reported. It is therefore recommended that the use of Arecoline be cycled in a 2 - 4 week on, 2 - 4 week off fashion. 

5.How Much Does It Cost?

Pre-workout supplements containing Arecoline, range anywhere from $2.00 to $4.00 per serve, depending on the size and quality of the product. 

Based on an average price of $3.00 per serve, and based on four serves per week, supplementing with pre-workout products containing Arecoline will typically cost around $48 per month.

6.What Are The Top Products?

We recommend using a pre-workout supplement such as Dynamik Muscle Savage Roar or Run Everything Labs Enter With Purpose. These products contain only the highest quality Arecoline (ArcoFuel) compound and are some of the best priced products on the Australian market.

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