Creatinol-O-Phosphate

1.What Is It?

Creatinol-O-Phosphate, scientifically known as N-methyl-N-(beta-hydroxyethyl)guanidine o-phosphate, is a synthetic analogue of Creatine. It is often mistaken as being a substitute for the Creatine, however it should be viewed as a completely separate compound as it provides completely different effects to Creatine. Creatinol-O-Phosphate was originally created for its ability to work as a cardioprotective drug whilst also being used to treat irregular heartbeats. It has become increasingly popular as a performance enhancing supplement in the health & fitness industry due to its ability to prolong Anaerobic Glycolysis.

2.What Does It Do?

Creatinol-O-Phosphate acts as an intracellular buffer that prevents a rise in acidity (a drop in pH) within working muscles during Anaerobic Glycolysis. Anaerobic Glycolysis defines the process whereby glucose is transformed into lactate during times of limited oxygen availability (for example during exercise). It is useful for short term energy production for exercise lasting from 10 seconds to 2 minutes in duration in the presence of lactic acid.

When exercising, oxygen is required to break down glucose for energy. When insufficient oxygen is available a substance called lactate is produced, which can also be converted into energy in the absence of oxygen. However, the build-up of lactate can exceed the rate at which it is converted and used for energy, and cause muscle acidity levels to skyrocket in a bid to protect muscles from damage caused by such metabolic by-products such as Hydrogen Ions and Lactic Acid. This results in the burning sensation felt within working muscles, cramping and muscular fatigue, and is the usual catalyst for muscular failure.

By buffering this rise in muscle acidity, Creatinol-O-Phosphate allows muscular contractions to continue in the presence of Hydrogen Ions and Lactic Acid, which would otherwise cause muscular failure. As a result, a higher quantity of muscle fibres can be recruited and stimulated, especially those which have the highest potential for growth and often take the longest amount of time to be recruited.

Because of this muscular failure delaying effect, Creatinol-O-Phosphate is often combined with Beta-Alanine to provide a comprehensive solution to battling muscular failure.

3.When Do I Take It?

To take advantage of the performance enhancing benefits of Creatinol-O-Phosphate, it is best taken approximately 15-30 minutes prior to exercise. To ensure sufficient absorption, it should be accompanied with carbohydrates or some fast digesting proteins to ensure it can enter and saturate muscle cells. While the most efficacious dose is not yet certain, reports suggest that 2-3 grams is most effective.

4.How Long Does It Take To Work?

Creatinol-O-Phosphate will go to work as soon as it is absorbed and can enter muscle cells, hence why it is imperative to maximise its absorption by accompanying it with some carbohydrates or fast digesting proteins. You will notice an increase in muscular endurance and a reduction in the burning sensation felt within working muscles after your very first dose.

5.How Much Does It Cost?

Supplements containing Creatinol-O-Phosphate range anywhere from $2.33 to $3.50 per serve, depending on the size and dosage, and the other ingredients included in the product.

Based on an average price of $2.50 per serve, and assuming 5 serves per week, supplementing with Creatinol-O-Phosphate will typically cost around $50 per month.

6.What Are The Top Products?

If you after a complete pre-workout supplement which contains the full recommended dosage of Creatinol-O-Phosphate, we recommend Olympus Labs Conqu3r Unleashed. Alternatively, 5% Nutrition Kill It contains an acceptable dose, as does the high stimulant pre-workout supplement Run Everything Labs EWP.

 

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